Lodine (Etodolac)

What is Lodine?

This medicine is taken to reduce such symptoms as swelling, pain and joint stiffness caused by arthritis. Its use helps patients to do their normal daily activities, and it belongs to NSAIDs. Lodine works by blocking the production of specific natural substances in the human body responsible for inflammation. Sometimes, this medication is also prescribed to treat gout attacks.


Recommendations for Use

Take Lodine orally as directed by doctors, once a day with enough water. It’s not allowed to lie down for ten minutes after its use. To avoid upset stomach, take regular doses with milk, food and antacids. The right dosage is prescribed according to individual tolerance and condition. To prevent possible risk of stomach bleeding and other serious side effects, this medicine should be taken at lower doses and for a short period of time. Usually, it takes about 2 weeks to experience its full benefit.

Precautions and Contraindications

Before using Lodine, inform doctors whether you have any allergies to its components and tell them about your medical history. Your physician needs to know if you have such serious conditions as blood disorders, asthma, clotting issues, nasal polyps, heart diseases, hypertension, liver and stomach problems, kidney and intestinal complications, throat conditions, etc. Be sure to drink enough water when taking this medicine to prevent severe dehydration. Lodine may rarely make patients drowsy or dizzy, so it’s not advisable to drive or do any activities that require full alertness.

This medication also causes stomach bleeding, and regular drinking and smoking increases this risk. It may make some patients more sensitive to the sun, so they need to avoid prolonged sun exposure and wear protective clothes. Older patients are more sensitive to its side effects, especially heart and kidney problems, intestinal and stomach bleeding. Children, nursing mothers and pregnant women should be careful with its intake.

Drug Interactions

They should be avoided, because they may change the effectiveness of Lodine while increasing your risk of having serious side effects. It’s not allowed to start using any meds without doctor's approval. Some of the most common pharmaceutical products that may potentially interact with this medicine include ACE inhibitors, corticosteroids, angiotensin II receptor blockers, lithium, cidofovir and some others. Be careful when taking Lodine with other drugs that increase a risk of bleeding, including blood thinners, anti-platelet meds, warfarin, etc. Fever reducers and pain relievers are quite similar to this medication, so they should be avoided, too. Lodine also affects the results of certain lab tests.

Side Effects

This treatment is associated with certain side effects, but most of them are mild and occur rarely. For example, some patients who take Lodine may experience such mild symptoms as diarrhea, dizziness, drowsiness, nausea and upset stomach. If any of these signs become bothersome, contact your doctor at once. Serious adverse effects are very rare, and they include such severe symptoms as easy bleeding and bruising, sudden hearing changes, painful or difficult swallowing, mood and mental changes, sudden weight gain, swelling of hands and feet, unexplained stiff neck, urine and vision changes, unusual tiredness, etc. In very rare cases, its intake causes liver damage and allergic reactions characterized by such signs as itching, swelling, skin rash, difficulty breathing, drowsiness and severe dizziness.