Provera (Medroxyprogesterone)

What is Provera?

Provera is an innovative treatment with Medroxyprogesterone being an active ingredient and promoting the required effect. The active component of the medication is progestin, known as a female hormone that balances certain functions, such as menstrual periods and ovulation. As a result, Provera is administered as a remedy against irregular or absent menstrual periods, unusual uterine bleeding and others. Besides, the treatment is prescribed to patients, who are in a risk group of endometrial hyperplasia occurrence, especially during estrogen intake. Provera also works warning the overgrowth of the uterus lining in postmenstrual women undergoing estrogen hormone replacement therapy. Additionally, you can ask your physician about off-label Provera intake and possible side effects.


Recommendations for Use

Discuss Provera use with your doctor before the beginning of its intake. Make sure you have provided all the required information and the adjusted dose is safe. Take Provera just according to the prescription and similar instructions to experience only advantageous reactions without side effects. The treatment course lasts for a few days every month. Depending on the purpose of Provera intake, you should start the therapy on a definite day of your menstrual cycle. Frequent physical exams are required for patients using Provera.

Precautions and Contraindications

Do not start Provera administration without previous doctor’s consultation. Severe birth defects may be caused by the treatment. Pregnant and breastfeeding women cannot take the drug. Besides, the treatment course should not be used by patients allergic to Medroxyprogesterone or other ingredients of the medication. Do not take Provera if you have liver disorders, abnormal vaginal bleeding, blood clots, hormone-related cancer and other diseases. Additionally, special dose adjustment is required in case a person taking Provera has accompanied illnesses or health complications, such as asthma, lupus, thyroid problems, epilepsy, decreased calcium levels in the organism, increased blood pressure, heart-related diseases, migraine headache, etc.

Drug Interactions

Provera is a powerful treatment that significantly affects female organs and related functions. Thus, the medication should be administered in accordance with all the safety instructions. As Provera may interact with several other drugs, your healthcare specialist should be aware of all the other treatments you are using. Tell the doctor about prescription and generic drugs, pharmaceutical supplements, vitamins and minerals that may cause any complications if used together with Provera. The medication should not be combined with Aminoglutethimide, anti-seizure drugs, remedies, affecting the liver enzyme and others. Besides, the medication can lead to unusual results of medical tests. Warn your doctor about Provera use before any examinations.

Side Effects

Even correct Provera intake may result in numerous reactions. However, they are minor and will disappear after a few drug uses. Among common Provera side effects are insomnia, unexpected weight gain, premenstrual symptoms, vaginal discharge and itching, breast discharge and tenderness, acne, rashes, itching and others.

Call your healthcare specialist in case these complications aggravate and launch more dangerous reactions, such as symptoms of blood clot in the leg or lung, symptoms of stroke, depression, fever, swelling, jaundice, breast lump, confusion, lightheadedness, etc. Seek emergency medical help as soon as you notice any signs of allergic reactions after Provera administration.