Prograf (Tacrolimus)

What is Prograf?

Prograf is a clinically studied and approved medication to decrease the immune system. Serving an active ingredient, Tacrolimus weakens the immune system of the patient, helping him/her after organ transplantation. The medication prevents body’s perception of a transplanted organ as an invader. Consequently, Prograf is prescribed for people who have had kidney, heart or liver transplantation. Additionally, the treatment can be used for other conditions not mentioned in the safety information.


Recommendations for Use

Consult your healthcare provider before Prograf administration and follow the adjusted instructions in order to get the desirable health improvement and avoid any risks. The drug should be taken for a complete length of adjusted therapy for a patient to experience the maximal benefit. Taking Prograf in higher doses advances your chance to suffer from bothersome and dangerous side effects. The drug should be used once each 12 hours, approximately at the same time daily. You can use Prograf with or without food. It is up to the healthcare provider to change the dose in accordance with the progress of the treatment course. Frequent blood tests are inevitable for a safe and successful therapy, since it helps to track the process. Contact your physician in case you have other questions concerning Prograf use.

Precautions and Contraindications

Patients, who are sensitive to Tacrolimus or other ingredients of the medication, should avoid the drug intake, as well as pregnant and breastfeeding women. The drug administration may increase the risk of certain complications occurrence, especially skin cancer, lymphoma, severe infections and other disorders. Follow the safety instructions to get a maximally safe therapy. Warn your doctor about other health impairments, diseases and abnormalities you have, in order to adjust the correct dose, suiting your condition. Special dose is required for people with liver or kidney problems, history of long QT syndrome, high blood pressure, heart-related disorders and others.

Drug Interactions

Serious kidney problems may occur if Prograf is used together with other pharmaceuticals. Interacting with other remedies, Prograf can cause a range of significant impairments and disorders. Due to this fact, your healthcare specialist should be aware of all the other prescription and generic drugs, herbal supplements and products you use. Warn your healthcare provider about chemotherapy, bowel disorder treatment, antivirals, injectable osteoporosis medication or antibiotics, arthritis drugs, hepatitis C medicines, Amiodarone, Nelfinavir, Cyclosporine, Sirolimus and others.

Side Effects

Despite of a potential positive impact of Prograf, it can also trigger serious health complications, especially if misused or overused. Seek emergency medical assistance to eliminate the symptoms of allergic reactions and possible consequences. Additionally, Prograf misuse can activate other life-threatening conditions that may appear during the medication intake. Stop using the treatment if you have got any signs of the infection. Besides, let your healthcare provider know about other complications and abnormalities bothering you during the course, especially swelling and pain near the organ that was transplanted, increased blood pressure, decreased level of phosphate or potassium, abnormal phosphate range, speech or vision disorders, urination disorders, issues with the central nervous system, symptoms of stomach bleeding and other serious impairments. Besides, pay attention to minor side effects, such as weakness, fatigue, tremors, swelling, diarrhea, nausea, kidney disorders, etc.